Lupus nephritis is a significant and serious disorder that often affects individuals with systemic lupus erythematosus (SLE), commonly known as Lupus. Lupus, an autoimmune disease, causes the body’s immune system to attack its cells and organs, including the kidneys. This attack results in a type of kidney disease called lupus nephritis, which can progress over time and potentially lead to kidney failure.
Lupus nephritis occurs when lupus autoantibodies target parts of the kidneys responsible for filtering waste. This autoimmune attack leads to inflammation, swelling, and irritation of the kidneys. Key symptoms include:
The American College of Rheumatology (ACR) classifies this disorder based on specific criteria such as proteinuria (protein in the urine) and the presence of urinary cellular casts.
Both children and adults with lupus can develop lupus nephritis. However, certain groups are more prone to this condition:
To diagnose this disorder, doctors utilize a combination of urine and blood tests, along with a kidney biopsy:
The main aim of treating lupus nephritis is to decrease inflammation and calm down the immune system to protect the kidneys from more damage. Common treatments include:
Managing lupus nephritis involves paying attention to diet. Patients are typically encouraged to limit their sodium intake to help manage blood pressure. It’s beneficial to collaborate with a dietitian to create a nutritious eating plan that promotes kidney health.
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Without proper diagnosis and treatment, this disorder can lead to severe complications, including kidney failure. Approximately 10 to 30 percent of individuals with this disorder may develop kidney failure, requiring dialysis or a kidney transplant. Other potential complications include increased risks of cancer (especially B-cell lymphoma) and cardiovascular problems.
Women with this disorder face higher risks during pregnancy, including preeclampsia, premature labour, and lupus flares. Monitoring and managing this disease carefully during pregnancy is crucial for the health of both the mother and the baby. Lets know more about the possibilities of pregnancy with kidney disease from the following blog 👇👇
Effectively managing this disorder involves consistently taking medications, making lifestyle adjustments, and attending regular medical appointments. Patients must maintain close communication with healthcare providers to monitor their condition closely and make any necessary treatment modifications.
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